/
/
Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
Se requiere una suscripción a JoVE para ver este contenido. Inicie sesión o comience su prueba gratuita.
Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
12,073 Views
•
11:45 min
•
November 14, 2013
DOI:
1Division of Biology,California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology,Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences,Johns Hopkins University School of Medicine, 4Department of Radiation Oncology,University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center,Johns Hopkins University School of Medicine
Summary
Automatically generated
The function of adult-born mammalian neurons remains an active area of investigation. Ionizing radiation inhibits the birth of new neurons. Using computer tomography-guided focal irradiation (CFIR), three-dimensional anatomical targeting of specific neural progenitor populations can now be used to assess the functional role of adult neurogenesis.
Read Article
Cite this Article
Lee, D. A., Salvatierra, J., Velarde, E., Wong, J., Ford, E. C., Blackshaw, S. Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition. J. Vis. Exp. (81), e50716, doi:10.3791/50716 (2013).
Copy