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Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue
JoVE Journal
Nörobilim
This content is Free Access.
JoVE Journal Nörobilim
Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue

Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue

DOI:

11:31 min

February 11, 2013

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Bölümler

  • 00:05Başlık
  • 02:12Brain Removal with In situ Devices
  • 05:17Tissue Processing and Clearing
  • 07:05Panorama Imaging of Full Tissue and Device Interface
  • 09:26Results: Intact Histological Characterization of Brain-implanted Microdevices and Surrounding Tissue
  • 10:51Conclusion

Özet

Otomatik Çeviri

Here we present a histological method for capturing, labeling, optically clearing, and imaging the intact brain tissue interface around chronically implanted microdevices in rodent brain tissue. Results from the techniques comprising this method are useful for understanding the impact of various penetrating brain-implants on their surrounding tissue.

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