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07:11 min
September 28, 2022
DOI:
10.3791/64289-v
This protocol presents the synthesis of cyclic peptides via bisalkylation between cysteine and methionine and the facile thiol-yne reaction triggered by the propargyl sulfonium center.
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Song, C., Hou, Z., Jiao, Z., Liu, Z., Lian, C., Zhang, M., Liang, W., Yin, F., Li, Z. Constructing Cyclic Peptides Using an On-Tether Sulfonium Center. J. Vis. Exp. (187), e64289, doi:10.3791/64289 (2022).
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