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Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain
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Neurociência
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JoVE Journal Neurociência
Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain

Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain

2,707 Views

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09:00 min

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April 28, 2022

DOI:

10.3791/63816-v

DOI:
10.3791/63816-v

•

09:00 min
April 28, 2022

•

4 Views
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1Department of Neurology,Northwestern University Feinberg School of Medicine

Tags

Amyloid FibrilsAmyloid PlaquesAlzheimer’s DiseaseProtein PurificationProteomic CharacterizationHomogenizationSucrose GradientProtein AggregatesProtein Deposits

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Cite this Article

Upadhyay, A., Vassar, R. J., Savas, J. N. Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain. J. Vis. Exp. (182), e63816, doi:10.3791/63816 (2022).

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