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JoVE Journal Developmental Biology
Gehirnorganoid-Erzeugung aus induzierten pluripotenten Stammzellen in hausgemachten Mini-Bioreaktoren
 
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Gehirnorganoid-Erzeugung aus induzierten pluripotenten Stammzellen in hausgemachten Mini-Bioreaktoren

Article DOI: 10.3791/62987-v • 10:16 min • December 11th, 2021
December 11th, 2021 •
1,3, 1,2, 1, 1,5, 1, 4, 4, 1,3, 1,3, 1,3
1Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical Biological Agency, 2Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 3Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine, Federal Medical Biological Agency, 4Department of Pathological Anatomy, North-Western State Medical University, 5Department of Biology, Lomonosov State University

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Hier beschreiben wir ein Protokoll zur Erzeugung von Hirnorganoiden aus humanen induzierten pluripotenten Stammzellen (iPS-Zellen). Um Gehirnorganoide in großen Mengen und von hoher Qualität zu erhalten, verwenden wir hausgemachte Mini-Bioreaktoren.

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Entwicklungsbiologie Heft 178
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