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实时活体内多光子显微镜可可视化聚焦超声和微气泡处理，以提高血脑屏障通透性
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February 05, 2022
DOI:
1Physical Sciences Platform,Sunnybrook Research Institute, 2Institute of Biomedical Engineering,University of Toronto, 3Department of Physics,Norwegian University of Science and Technology, 4Department of Clinical Medicine,University of Bergen, 5Exact Therapeutics AS, 6Department of Medical Biophysics,University of Toronto
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该协议描述了在聚焦超声和微气泡治疗期间能够对啮齿动物大脑进行实时 体内 多光子荧光成像的外科和技术程序，以增加血脑屏障通透性。
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Poon, C., Mühlenpfordt, M., Olsman, M., Kotopoulis, S., de Lange Davies, C., Hynynen, K. Real-Time Intravital Multiphoton Microscopy to Visualize Focused Ultrasound and Microbubble Treatments to Increase Blood-Brain Barrier Permeability. J. Vis. Exp. (180), e62235, doi:10.3791/62235 (2022).
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