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JoVE Journal Neuroscience
Målrettet neuronal skade for ikke-invasiv afbrydelse af hjernen kredsløb
 
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Målrettet neuronal skade for ikke-invasiv afbrydelse af hjernen kredsløb

Article DOI: 10.3791/61271-v • 10:58 min • September 27th, 2020
September 27th, 2020 •
*1, *2, 1, 3, 1,4, 5, 6, *2, *1,7,8
1Department of Neuroscience, University of Virginia, 2Department of Radiology, Stanford University, 3Department of Neurology, University of Virginia, 4Global Internship Program, Focused Ultrasound Foundation, 5Department of Medicine, University of Virginia, 6Image Guided Therapy, 7Department of Neurosurgery, University of Virginia, 8Center for Brain, Immunology, and Glia, University of Virginia
* These authors contributed equally

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Målet med protokollen er at give en metode til fremstilling af ikke-invasive neuronale læsioner i hjernen. Metoden udnytter Magnetic Resonance-guidet Fokuseret ultralyd (MRgFUS) til at åbne Blodhjernen Barrier i en forbigående og fokal måde, for at levere en cirkulerende neurotoksin til hjernen parenkym.

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Neurovidenskab Problem 163 Fokuseret ultralyd ikke-invasiv neurokirurgi neuronal læsion MR hjerne
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