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用于调节人类供体后段眼内压和颅内压的跨层自主系统模型
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Neurociência
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JoVE Journal Neurociência
Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
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用于调节人类供体后段眼内压和颅内压的跨层自主系统模型

DOI:
10.3791/61006-v

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08:55 min

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April 24, 2020

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, , ,
1North Texas Eye Research Institute, Department of Pharmacology and Neuroscience,University of North Texas Health Science Center, 2Mechanical Engineer Consultant, 3Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health,University of Wisconsin

Capítulos

  • 00:05Introduction
  • 00:44Translaminar Autonomous System (TAS) Setup
  • 01:42Human Whole Eye Globe Preparation
  • 02:24IOP (Bottom) Chamber Setup
  • 03:20ICP (Top) Chamber Setup
  • 03:52Data Recording System Setup
  • 06:56Results: Representative Translaminar Autonomous System Model Analyses
  • 08:26Conclusion

Summary

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我们描述并详细介绍了跨层自治系统的使用。该系统利用人后段独立调节节段（眼内）内和视神经周围（颅内）的压力，以产生模仿青光眼性视神经病变特征的跨层压力梯度。

Tags

Translaminar Autonomous SystemIntraocular PressureIntracranial PressurePosterior SegmentEx VivoPreclinicalGlaucomaTraumatic Brain InjuryIdiopathic Intracranial HypertensionSpaceflight-associated Neuro-ocular SyndromePerfusion FluidSyringeFilterTubingOptic NerveVitreous HumorRetinaEpoxy ResinO-ringScrewsIOP Chamber

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