Dergi
/
Nörobilim
/
Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
JoVE Journal
Nörobilim
Bu içeriği görüntülemek için JoVE aboneliği gereklidir.  Oturum açın veya ücretsiz deneme sürümünü başlatın.
JoVE Journal Nörobilim
Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

DOI:
10.3791/61006-v

•

08:55 min

•

April 24, 2020

•

, , ,
1North Texas Eye Research Institute, Department of Pharmacology and Neuroscience,University of North Texas Health Science Center, 2Mechanical Engineer Consultant, 3Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health,University of Wisconsin

Bölümler

  • 00:05Introduction
  • 00:44Translaminar Autonomous System (TAS) Setup
  • 01:42Human Whole Eye Globe Preparation
  • 02:24IOP (Bottom) Chamber Setup
  • 03:20ICP (Top) Chamber Setup
  • 03:52Data Recording System Setup
  • 06:56Results: Representative Translaminar Autonomous System Model Analyses
  • 08:26Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

We describe and detail the use of the translaminar autonomous system. This system utilizes the human posterior segment to independently regulate the pressure inside the segment (intraocular) and surrounding the optic nerve (intracranial) to generate a translaminar pressure gradient that mimics features of glaucomatous optic neuropathy.

Etiketler

Translaminar Autonomous SystemIntraocular PressureIntracranial PressurePosterior SegmentEx VivoPreclinicalGlaucomaTraumatic Brain InjuryIdiopathic Intracranial HypertensionSpaceflight-associated Neuro-ocular SyndromePerfusion FluidSyringeFilterTubingOptic NerveVitreous HumorRetinaEpoxy ResinO-ringScrewsIOP Chamber

Article

Embed

ÇALMA LİSTESİNE EKLE

Usage Statistics

İlgili Videolar

Time-lapse Live Imaging of Clonally Related Neural Progenitor Cells in the Developing Zebrafish Forebrain

Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction

The Olfactory System as a Model to Study Axonal Growth Patterns and Morphology In Vivo

Enrichment of Bruch’s Membrane from Human Donor Eyes

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa

Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software

How to Obtain Reliable Visual Event-related Potentials in Newborns

3D Kinematic Analysis for the Functional Evaluation in the Rat Model of Sciatic Nerve Crush Injury

Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure

Read Article