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使用有条件Cas9稳定评估基因功能的新工具包
 
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使用有条件Cas9稳定评估基因功能的新工具包

Article DOI: 10.3791/60685-v • 08:20 min • September 2nd, 2021
September 2nd, 2021 •
1,2, 1
1Cold Spring Harbor Laboratory, 2Faculty of Pharmacy, University of Ljubljana

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在这里，我们描述了一个基因组编辑工具，基于时间和条件稳定聚类定期间歇性短腹膜重复（CRISPR-）相关蛋白质9（Cas9）下的小分子，盾牌-1。该方法可用于培养细胞和动物模型。

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遗传学， 第 175 期， 基因编辑， 功能基因组研究， CRISPR， Cas9， 破坏稳定的领域， 诱导
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