Journal
/
Biologia do Desenvolvimento
/
Realización de Xenoinjertos musculares esqueléticos humanos en ratones inmunodeficientes
JoVE Journal
Biologia do Desenvolvimento
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Biologia do Desenvolvimento
Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice
Please note that all translations are automatically generated. Click here for the English version.

Realización de Xenoinjertos musculares esqueléticos humanos en ratones inmunodeficientes

9,446 Views

•

07:48 min

•

September 16, 2019

DOI:

10.3791/59966-v

DOI:
10.3791/59966-v

•

07:48 min
September 16, 2019

•

10 Views
, , ,
1Graduate Program in Cellular and Molecular Medicine,Johns Hopkins University School of Medicine, 2Department of Neurology,Johns Hopkins University School of Medicine, 3Kennedy Krieger Institute, 4Department of Neuroscience,Johns Hopkins University School of Medicine

Summary

Automatically generated

Las enfermedades humanas complejas pueden ser difíciles de modelar en los sistemas de modelos de laboratorio tradicionales. Aquí, describimos un enfoque quirúrgico para modelar la enfermedad muscular humana a través del trasplante de biopsias musculares esqueléticas humanas en ratones inmunodeficientes.

Explore More Videos

Human Skeletal Muscle XenograftsImmunodeficient MiceMuscle Disease ModelingPreclinical Therapeutic TestingHuman Muscle Cell BiologyRare Or Acquired Muscle DiseasesMuscle BiopsyNOD-Rag-gamma MouseTibialis AnteriorExtensor Digitorum LongusPeroneus LongusSurgical Procedure

Read Article

Cite this Article

Britson, K. A., Black, A. D., Wagner, K. R., Lloyd, T. E. Performing Human Skeletal Muscle Xenografts in Immunodeficient Mice. J. Vis. Exp. (151), e59966, doi:10.3791/59966 (2019).

Download .ris file

Copy

Share Video

.

Copy