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Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
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JoVE Journal Genética
Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

8,696 Views

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11:13 min

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April 10, 2018

DOI:

10.3791/57442-v

DOI:
10.3791/57442-v

•

11:13 min
April 10, 2018

•

7 Views
, , ,
1IVI-RMA New Jersey, 2Jefferson College of Biomedical Sciences,Thomas Jefferson University, 3Department of Genetics,Rutgers, The State University of New Jersey

Summary

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As the genetic variants associated with human disease begin to become uncovered, it is becoming increasingly important to develop systems with which to rapidly evaluate the biological significance of those identified variants. This protocol describes methods for evaluating human gene function during female meiosis I using mouse oocytes.

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Cite this Article

Marin, D., Nguyen, A. L., Scott, Jr., R. T., Schindler, K. Using Mouse Oocytes to Assess Human Gene Function During Meiosis I. J. Vis. Exp. (134), e57442, doi:10.3791/57442 (2018).

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