Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

Diego Marin; Alexandra L. Nguyen; Richard T. Scott, Jr.; Karen Schindler

doi:10.3791/57442

ジャーナル

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遺伝学

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Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

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遺伝学

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JoVE Journal 遺伝学

Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

8,696 Views

•

11:13 min

•

April 10, 2018

DOI:

10.3791/57442-v

DOI:

10.3791/57442-v

•

11:13 min

April 10, 2018

•

7 Views

Diego Marin*^1,2, Alexandra L. Nguyen*³, Richard T. Scott, Jr.^1,2, Karen Schindler³

¹IVI-RMA New Jersey, ²Jefferson College of Biomedical Sciences,Thomas Jefferson University, ³遺伝学科,Rutgers, The State University of New Jersey

概要

As the genetic variants associated with human disease begin to become uncovered, it is becoming increasingly important to develop systems with which to rapidly evaluate the biological significance of those identified variants. This protocol describes methods for evaluating human gene function during female meiosis I using mouse oocytes.

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Using Mouse Oocytes to Assess Human Gene Function During Meiosis I

概要

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