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Een<em> In Vitro</em> Caseum Binding Assay die de penetratie van drugs in tuberculose-lesingen voorspelt
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Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
An In Vitro Caseum Binding Assay that Predicts Drug Penetration in Tuberculosis Lesions
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Een<em> In Vitro</em> Caseum Binding Assay die de penetratie van drugs in tuberculose-lesingen voorspelt

11,457 Views

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12:17 min

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May 08, 2017

DOI:

10.3791/55559-v

DOI:
10.3791/55559-v

•

12:17 min
May 08, 2017

•

5 Views
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1Public Health Research Institute Centre, New Jersey Medical School,Rutgers, 2Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, NIAID,NIH

Summary

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Hier beschrijven we een werkwijze snel evenwicht dialyse (RED) drug binding aan ca- seum longtuberculose laesies en holtes meten. Het protocol wordt ook gebruikt met een schuimige-macrofaag afgeleide matrix met een effectieve surrogaat voor ca- seum.

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Cite this Article

Sarathy, J. P., Liang, H. H., Weiner, D., Gonzales, J., Via, L. E., Dartois, V. An In Vitro Caseum Binding Assay that Predicts Drug Penetration in Tuberculosis Lesions. J. Vis. Exp. (123), e55559, doi:10.3791/55559 (2017).

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