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Imunologia e Infecção

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遗传操纵<em>Δku80</em>株功能基因组分析<em>弓形虫</em

JoVE Journal
Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

Genetic Manipulation in Δku80 Strains for Functional Genomic Analysis of Toxoplasma gondii

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遗传操纵<em>Δku80</em>株功能基因组分析<em>弓形虫</em

16,699 Views

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09:52 min

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July 12, 2013

DOI:

10.3791/50598-v

DOI:

10.3791/50598-v

•

09:52 min

July 12, 2013

•

6 Views

Leah M. Rommereim¹, Miryam A. Hortua Triana¹, Alejandra Falla¹, Kiah L. Sanders¹, Rebekah B. Guevara¹, David J. Bzik¹, Barbara A. Fox¹

¹Department of Microbiology and Immunology,The Geisel School of Medicine at Dartmouth

Summary

在这里，我们报道了一种采用I型和II型<em>Δku80</em菌株<em>弓形虫</em>高效的生成有针对性的基因缺失和基因替换为功能基因组学分析。

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