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使用黑色素瘤和鳞状癌干细胞生成新型支气干细胞疫苗
JoVE Journal
Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
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使用黑色素瘤和鳞状癌干细胞生成新型支气干细胞疫苗

DOI:
10.3791/50561-v

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12:43 min

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January 06, 2014

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, , , , , , , , ,
1Department of Surgery,University of Michigan, 2Department of Internal Medicine,University of Michigan, 3Department of Otolaryngology,University of Michigan

Capítulos

  • 00:05Título
  • 02:12ALDEFLUOR Staining
  • 04:45Preparation of Cancer Stem Cell Lysate-pulsed Dendritic Cell (CSC-TPDC) Vaccine
  • 07:11Vaccination and Evaluation of the Efficacy
  • 09:07Results: CSC-TPDC Vaccination Significantly Inhibits Murine Tumor Growth Activity
  • 12:07Conclusion

Summary

Tadução automática

Tadução automática

在合成免疫能力宿主中评估，基于癌症干细胞 （CSC） 的树突状细胞 （DC） 疫苗的抗肿瘤免疫力明显高于使用异质散装肿瘤细胞脉冲的传统 DC 疫苗。

Tags

Keywords: Cancer Stem CellsDendritic Cell VaccineMelanomaSquamous CancerALDHAntitumor ImmunityIFN-γGM-CSF

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