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自体血液的注入模型小鼠自发性脑出血

JoVE Journal
Neurociência

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JoVE Journal Neurociência

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

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自体血液的注入模型小鼠自发性脑出血

DOI:

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07:02 min

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August 24, 2011

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Lauren H. Sansing^2,3, Scott E. Kasner, Louise McCullough, Puneet Agarwal, Frank A. Welsh, Katalin Kariko

¹Department of Neurology,University of Connecticut Health Center, ²Department of Neurology,School of Medicine, University of Pennsylvania, ³Department of Neurosurgery,Hartford Hospital, ⁴Department of Neurosurgery,School of Medicine, University of Pennsylvania

Capítulos

01:11Pre-operative Procedures
02:31Intracerebral Hemorrhage Surgery
05:42Surgical Success Rate and Behavioral Analysis
06:27Conclusion

Summary

Tadução automática

自体血注射在本议定书中所描述的小鼠脑出血模型，采用双色注塑技术，以最大限度地减少了针轨道，在泵送系统中没有抗凝血剂的血液回流的风险，并消除了所有死在空间和系统扩展的油管。

Tags

Autologous Blood Injection Spontaneous Intracerebral Hemorrhage Mice Model Pathophysiology Of Injury Intracerebral Hemorrhage Reproducible Animal Model Effective Therapy Stereotaxic Injection Arterial Blood Basal Ganglia Spontaneous Hypertensive Hemorrhage Neurobehavioral Deficits Potential Therapeutic Agents Double Injection Technique Blood Reflux Anticoagulants Dead Space Expandable Tubing

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