A normothermic ex vivo liver perfusion (NEVLP) system was created for mouse livers. This system requires experience in microsurgery but allows for reproducible perfusion results. The ability to utilize mouse livers facilitates the investigation of molecular pathways to identify novel perfusate additives and enables the execution of experiments focused on organ repair.
Chen, H., Dirsch, O., Albadry, M., Ana, P. H., Dahmen, U. Normothermic Ex Vivo Liver Machine Perfusion in Mouse. J. Vis. Exp. (199), e65363, doi:10.3791/65363 (2023).