需要订阅 JoVE 才能查看此. 登录或开始免费试用。
Normothermic Ex Vivo Liver Machine Perfusion in Mouse
1,832 Views
•
13:14 min
•
September 25, 2023
DOI:
Summary
Automatically generated
A normothermic ex vivo liver perfusion (NEVLP) system was created for mouse livers. This system requires experience in microsurgery but allows for reproducible perfusion results. The ability to utilize mouse livers facilitates the investigation of molecular pathways to identify novel perfusate additives and enables the execution of experiments focused on organ repair.
Explore More Videos
NormothermicEx-vivoLiverMachine PerfusionMouseMolecular MechanismsGenetically Modified AnimalsTransgenic MiceThermostatic ControllerPeristaltic PumpOxygenatorBubble TrapPortal VeinSuprahepatic CavaBile DrainageSemi-sterile30G Needle26G CatheterHeparinized SalineOrgan ChamberRoller PumpHeat Exchanger
Read Article
Cite this Article
Chen, H., Dirsch, O., Albadry, M., Ana, P. H., Dahmen, U. Normothermic Ex Vivo Liver Machine Perfusion in Mouse. J. Vis. Exp. (199), e65363, doi:10.3791/65363 (2023).
Copy