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Measuring Ubiquitylated, SUMOylated, and ADP-Ribosylated DNA-Protein Crosslinks
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Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications
JoVE 신문
생화학
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JoVE 신문 생화학
Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications

Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications

1,132 Views

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03:20 min

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April 21, 2023

DOI:

10.3791/65315-v

DOI:
10.3791/65315-v

•

03:20 min
April 21, 2023

•

17 Views
1Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute,National Institutes of Health

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DNA-protein CrosslinksDNA Damage RepairTopoisomerase InhibitorsPARP InhibitorsAldehydesPost-translational ModificationsDeubiquitylationSUMOylationADP-ribosylationIn Vivo Complex Of Enzyme AssayRapid Approach To DNA Adduct Recovery AssayImmunofluorescenceQuantitationKineticsFormation

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Sun, Y. Quantitative Detection of DNA-Protein Crosslinks and Their Post-Translational Modifications. J. Vis. Exp. (194), e65315, doi:10.3791/65315 (2023).

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