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大鼠胫神经瘤转位模型中的手术和行为测试

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Surgery and Behavioral Testing in the Tibial Neuroma Transposition Model in Rats

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大鼠胫神经瘤转位模型中的手术和行为测试

1,544 Views

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07:23 min

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January 06, 2023

DOI:

10.3791/64659-v

DOI:

10.3791/64659-v

•

07:23 min

January 06, 2023

•

18 Views

Elisabeth Maria Brakkee¹, Erick DeVinney², Niels Eijkelkamp³, J. Henk Coert¹

¹Department of Plastic and Reconstructive Surgery,University Medical Center Utrecht, Utrecht University, ²Axogen, ³Center for Translational Immunology,University Medical Center Utrecht, Utrecht University

Summary

该协议描述了胫神经瘤转位模型，该模型需要胫神经病变，随后近端神经末梢向皮下胫前或外侧位置转位。神经瘤疼痛和足底痛觉过敏的行为测试使用冯弗雷单丝进行定量。

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