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Surgery and Behavioral Testing in the Tibial Neuroma Transposition Model in Rats
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January 06, 2023
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This protocol describes the tibial neuroma transposition model, which entails a lesion of the tibial nerve with subsequent transposition of the proximal nerve end toward a subcutaneous pretibial or lateral position. Behavioral testing of neuroma pain and plantar hyperalgesia is quantified using Von Frey monofilaments.
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Brakkee, E. M., DeVinney, E., Eijkelkamp, N., Coert, J. H. Surgery and Behavioral Testing in the Tibial Neuroma Transposition Model in Rats. J. Vis. Exp. (191), e64659, doi:10.3791/64659 (2023).
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