This protocol describes how to measure contractility in adult human primary cardiomyocytes from donor hearts with the MyoBLAZER system, a reliable platform for assessing drug-induced changes in contractility during preclinical development.
Abi Gerges, N., Stafford, A., Truong, K., Miron, Y., Winrow, B., Krause, B., Page, G., Ghetti, A. Measurement of Heart Contractility in Isolated Adult Human Primary Cardiomyocytes. J. Vis. Exp. (186), e64394, doi:10.3791/64394 (2022).