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Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
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Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

2,189 Views

08:25 min

September 26, 2022

DOI:

08:25 min
September 26, 2022

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Summary

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Contact hypersensitivity (CHS) is a murine experimental model of allergic contact dermatitis (ACD). CHS is based on sensitization with reactive hapten by painting the shaved skin of the chest and abdomen, with a subsequent ear skin challenge with a diluted hapten, causing a swelling reaction that is assessed in various ways.

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