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通过电感耦合等离子体质谱法对斑马鱼中铂基和钌基化合物暴露的剂量吸收，具有更广泛的应用
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Dose Uptake of Platinum- and Ruthenium-based Compound Exposure in Zebrafish by Inductively Coupled Plasma Mass Spectrometry with Broader Applications
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通过电感耦合等离子体质谱法对斑马鱼中铂基和钌基化合物暴露的剂量吸收，具有更广泛的应用

DOI:
10.3791/63587-v

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08:46 min

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April 21, 2022

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, , , , ,
1Environmental and Occupational Health Sciences Institute,Rutgers University, 2Department of Biochemistry and Microbiology,Rutgers University, 3Centro de Química Estrutural and Departamento de Química e Bioquímica, Faculdade de Ciências,Universidade de Lisboa

Chapters

  • 00:04Introduction
  • 00:44Tissue Digestion and ICPMS Evaluation
  • 06:13Results: Assessment of Lethality and Delayed Hatching of Zebrafish
  • 08:09Conclusion

Summary

자동 번역

자동 번역

斑马鱼中金属和金属基化合物的药代动力学和毒代动力学分析速率的提高对于环境和临床转化研究是有利的。通过使用电感耦合等离子体质谱对消化的斑马鱼组织进行痕量金属分析，克服了未知水性暴露摄取的局限性。

Tags

ZebrafishDose UptakePlatinumRutheniumInductively Coupled Plasma Mass Spectrometry (ICPMS)Matrix-matched CalibrationIsobaric InterferenceMetal ExposurePharmacologyEnvironmental Science

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