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Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery
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May 24, 2021
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Different models of middle cerebral artery occlusion (MCAo) are used in experimental stroke research. Here, an experimental stroke model of transient MCAo via the external carotid artery (ECA) is described, which aims to mimic human stroke, in which the cerebrovascular thrombus is removed due to spontaneous clot lysis or therapy.
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Llovera, G., Simats, A., Liesz, A. Modeling Stroke in Mice: Transient Middle Cerebral Artery Occlusion via the External Carotid Artery. J. Vis. Exp. (171), e62573, doi:10.3791/62573 (2021).
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