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In-Nucleus Hi-C in Drosophila Cells
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September 15, 2021
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Summary
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The genome is organized in the nuclear space into different structures that can be revealed through chromosome conformation capture technologies. The in-nucleus Hi-C method provides a genome-wide collection of chromatin interactions in Drosophila cell lines, which generates contact maps that can be explored at megabase resolution at restriction fragment level.
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Esquivel-López, A., Arzate-Mejía, R., Pérez-Molina, R., Furlan-Magaril, M. In-Nucleus Hi-C in Drosophila Cells. J. Vis. Exp. (175), e62106, doi:10.3791/62106 (2021).
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