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JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Detectie van microRNA-expressie in de nieren van immunoglobuline A nefropathische muizen
 
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Detectie van microRNA-expressie in de nieren van immunoglobuline A nefropathische muizen

Article DOI: 10.3791/61535-v • 05:39 min • July 8th, 2020
July 8th, 2020 •
1, 1, 1, 1,2, 1, 1, 1, 3, 1
1Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 2Division of Intensive Care Unit, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 3Department of Medical Physiology, Meiji Pharmaceutical University

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microRNA's zijn betrokken bij de pathogenese van IgA-nefropathie. We hebben een betrouwbare methode ontwikkeld voor het detecteren van microRNA-expressieniveaus in de nieren van een IgA-nefropathiemuismodel (HIGA-muizen). Deze nieuwe methode zal het gemakkelijker maken om te controleren op betrokkenheid van miRNA's bij IgA-nefropathie.

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Deze maand in JoVE Nummer 161 microRNA IgA-nefropathie HIGA-muis qRT-PCR nier expressie
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