The method describes inflammation-sensitized hypoxic-ischemic and hyperoxic brain injury in the P17 ferret to model the complex interaction between prolonged inflammation and oxidative brain injury experienced in a number of late preterm infants.
Wood, T., Moralejo, D., Corry, K., Fisher, C., Snyder, J. M., Acuna, V., Holden-Hunt, A., Virk, S., White, O., Law, J., Parikh, P., Juul, S. E. A Ferret Model of Inflammation-sensitized Late Preterm Hypoxic-ischemic Brain Injury. J. Vis. Exp. (153), e60131, doi:10.3791/60131 (2019).