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LC-MCYMS 诊断碎裂过滤的天然产物发现: 微囊藻毒素分析的应用

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Natural Product Discovery with LC-MS/MS Diagnostic Fragmentation Filtering: Application for Microcystin Analysis

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LC-MCYMS 诊断碎裂过滤的天然产物发现: 微囊藻毒素分析的应用

DOI:

10.3791/59712-v

•

07:18 min

•

May 31, 2019

•

David R. McMullin, Shawn Hoogstra, Kimberlynn P. McDonald, Mark W. Sumarah², Justin B. Renaud

¹Department of Chemistry,Carleton University Ottawa, ²London Research and Development Center,Agriculture and Agri-Food Canada

Chapters

00:04Title
01:04Diagnostic Fragmentation Filtering (DFF) for Microcystin (MC) Analysis
03:37Non-Targeted Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Dataset Preparation
05:25Results: Representative DFF Plot for MC Analysis of M. aeruginosa Cellular Extract
06:45Conclusion

Summary

자동 번역

诊断碎片过滤, 实现到 MZmine, 是一种优雅的, 采集后的方法, 筛选 LC-MMSMS 数据集的整个类别的已知和未知的天然产品。此工具搜索 msms 光谱, 以查找分析师定义为诊断整个类别化合物的产品离子和中性损耗。

Tags

Natural Products Diagnostic Fragmentation Filtering LC-MS/MS Microcystin Cyanobacteria Toxin Analysis New Compound Discovery Software MZmine Mass Spectrometry Tandem Mass Spectrometry Sample Preparation

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