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人诱导多能干细胞体外生成体细胞衍生物的研究
JoVE 신문
발생학
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JoVE 신문 발생학
In Vitro Generation of Somite Derivatives from Human Induced Pluripotent Stem Cells
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人诱导多能干细胞体外生成体细胞衍生物的研究

DOI:
10.3791/59359-v

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06:21 min

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April 25, 2019

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, ,
1Department of Life Science Frontiers, Center for iPS Cells Research and Application,Kyoto University, 2Department of Clinical Application, Center for iPS Cells Research and Application,Kyoto University

Chapters

  • 00:04Title
  • 00:58Human Induced Pluripotent Stem Cell (iPSC) Pre-induction Preparation
  • 02:14Presomitic Mesoderm (PSM) and Somitic (SM) Differentiation
  • 03:20SM Derivative [Syndetome (SYN)] Differentiation
  • 04:28Results: Representative iPSC-derived Product Characterization
  • 05:44Conclusion

Summary

자동 번역

자동 번역

我们在这里提出了一个方案, 分化为每个体细胞衍生物 (肌细胞, 硬化体, 皮肤和合成) 在化学定义的条件下, 这在未来的疾病建模和骨科手术中基于细胞的治疗。

Tags

Keywords: Induced Pluripotent Stem CellsIPSCSomite DerivativesMyotomeDermatomeSclerotomeSyndetomeParaxial MesodermPresomitic MesodermDelta-like Protein 1Regenerative TherapyDisease ModelingMusculoskeletal DisorderHuman Embryogenesis

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