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Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats
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Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats

Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats

10,024 Views

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05:54 min

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April 04, 2019

DOI:

10.3791/59327-v

DOI:
10.3791/59327-v

•

05:54 min
April 04, 2019

•

15 Views
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1Department of Neurology,Harvard Medical School – Beth Israel Deaconess Medical Center, 2Department of Orthopaedics,Harvard Medical School – Beth Israel Deaconess Medical Center

Summary

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By using an innovative ground-based analogue model, we are able to simulate a space mission including a trip to (0 g) and a stay on Mars (0.38 g) in rats. This model allows for a longitudinal assessment of the physiological changes occurring during the two hypo-gravitational stages of the mission.

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Hindlimb UnloadingPartial Weight BearingRat ModelMars MissionPhysiological Changes행동분석학MemoryPerformanceStressGround-based ModelSpace ExplorationAnesthesiaSuspension Device

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Cite this Article

Mortreux, M., Riveros, D., Bouxsein, M. L., Rutkove, S. B. Mimicking a Space Mission to Mars Using Hindlimb Unloading and Partial Weight Bearing in Rats. J. Vis. Exp. (146), e59327, doi:10.3791/59327 (2019).

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