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微胶质细胞抗体介导的陶氏清除研究
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Cell-based Assay to Study Antibody-mediated Tau Clearance by Microglia
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微胶质细胞抗体介导的陶氏清除研究

7,976 Views

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07:18 min

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November 09, 2018

DOI:

10.3791/58576-v

DOI:
10.3791/58576-v

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07:18 min
November 09, 2018

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2 Views
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1Neuroscience Discovery,Janssen Pharmaceutical Company of Johnson & Johnson, Belgium, 2Department of Hematopoiesis,Sanquin Research and Landsteiner Laboratory, The Netherlands, 3Janssen Prevention Center,Janssen Pharmaceutical Company of Johnson & Johnson, The Netherlands, 4Neuroscience Discovery,Janssen Pharmaceutical Company of Johnson & Johnson, Pennsylvania

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Cell-based AssayAntibody-mediated Tau ClearanceMicrogliaAlzheimer’s DiseasePH Dye-Tau AggregatesAnti-Tau AntibodiesBV-2 CellsCell CultureTrypsin EDTACentrifugation

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De Marco, D., Taggenbrock, R., Crespo, R., Koudstaal, W., Ramsburg, E., Apetri, A. Cell-based Assay to Study Antibody-mediated Tau Clearance by Microglia. J. Vis. Exp. (141), e58576, doi:10.3791/58576 (2018).

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