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A Controlled Mouse Model for Neonatal Polymicrobial Sepsis
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January 27, 2019
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1Department of Experimental Medicine,University of British Columbia, 2Department of Pediatrics, Division of Infectious Diseases,University of British Columbia, 3Department of Pediatrics, College of Medicine,University of Florida, 4Department of Pathology, Immunology, and Laboratory Medicine,University of Florida
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This protocol provides the necessary steps to establish and evaluate neonatal sepsis in 7-day-old mice.
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Brook, B., Amenyogbe, N., Ben-Othman, R., Cai, B., Harbeson, D., Francis, F., Liu, A. C., Varankovich, N., Wynn, J., Kollmann, T. R. A Controlled Mouse Model for Neonatal Polymicrobial Sepsis. J. Vis. Exp. (143), e58574, doi:10.3791/58574 (2019).
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