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En roman In Vitro modell av Blast traumatisk hjärnskada
 
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En roman In Vitro modell av Blast traumatisk hjärnskada

Article DOI: 10.3791/58400-v • 08:59 min • December 21st, 2018
December 21st, 2018 •
1,2, 1, 2,3, 1, 4,5, 6, 1,2
1Anaesthetics, Pain Medicine and Intensive Care Section, Department of Surgery and Cancer, Imperial College London, 2Royal British Legion Centre for Blast Injury Studies, Department of Bioengineering, Imperial College London, 3Department of Bioengineering, Imperial College London, 4Department of Life Sciences, Imperial College London, 5Department of Anaesthetics, Royal Berkshire Hospital NHS Foundation Trust, 6Royal Centre for Defence Medicine, Medical Directorate Joint Force Command

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Detta dokument beskriver en ny modell av primära blast traumatisk hjärnskada. En tryckluft driven signalledares används för att exponera in vitro- mus Hippocampus slice kulturer till en enda chockvåg. Detta är en enkel och snabb protokoll som genererar en reproducerbar hjärnskada vävnad med ett högt dataflöde.

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Neurovetenskap fråga 142 Blast traumatisk hjärnskada primära blast skada blast-inducerad neurotrauma shock tube in vitro- modell TBI organotypic Hippocampus slice kulturer
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