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Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm
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Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm

Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm

11,227 Views

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08:29 min

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June 07, 2018

DOI:

10.3791/56983-v

DOI:
10.3791/56983-v

•

08:29 min
June 07, 2018

•

4 Views
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1Unidad de Investigación Psicobiología de las Drogodependencias, Departamento de Psicobiología, Facultad de Psicología,Universitat de València

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This protocol describes the Conditioned Place Preference (CPP) as a model of relapse. This procedure permits the measurement of relapse in laboratory animals, considering the impact of drug-associated environmental cues as craving and relapse in abstaining addicts is currently the focus of drug-abuse treatment programs.

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Drug-seekingReinstatementConditioned Place PreferenceCPPDrug AddictionRelapseEnvironmental CuesStressIncentive Motivational ValueEthologySocial DefeatHabituationCocaineMouse

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Cite this Article

Blanco-Gandía, M. C., Aguilar, M. A., Miñarro, J., Rodríguez-Arias, M. Reinstatement of Drug-seeking in Mice Using the Conditioned Place Preference Paradigm. J. Vis. Exp. (136), e56983, doi:10.3791/56983 (2018).

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