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Un enzima Split-TET2 ingegnerizzati per chimica-inducible DNA Hydroxymethylation e rimodellamento epigenetico
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December 18, 2017
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1Centre for Epigenetics and Disease Prevention, Department of Molecular and Cellular Medicine, Institute of Biosciences and Technology, College of Medicine,Texas A&M University, 2Centre for Translational Cancer Research, Department of Medical Physiology, Institute of Biosciences and Technology, College of Medicine,Texas A&M University
Summary
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Protocolli dettagliati per l'introduzione di un enzima derivati dal Spalato-TET2 (sidro) nelle cellule di mammiferi per chimica viscoelastica DNA hydroxymethylation e rimodellamento epigenetici sono presentati.
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Lee, M., Zhou, Y., Huang, Y. An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling. J. Vis. Exp. (130), e56858, doi:10.3791/56858 (2017).
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