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MOG35-55 诱发自身免疫性脑脊髓炎 C57BL/6 小鼠矢状面运动步态分析

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Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis

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MOG35-55 诱发自身免疫性脑脊髓炎 C57BL/6 小鼠矢状面运动步态分析

8,463 Views

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13:02 min

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November 04, 2017

DOI:

10.3791/56032-v

DOI:

10.3791/56032-v

•

13:02 min

November 04, 2017

•

4 Views

Maximillian DJ Fiander*¹, Matthew AJ Chedrawe*¹, Anna-Claire Lamport¹, Turgay Akay², George S Robertson^1,3

¹Pharmacology,Dalhousie University, ²Medical Neuroscience,Dalhousie University, ³Psychiatry,Dalhousie University

Summary

矢状面的运动学步态分析获得了关于如何执行运动的高度精确的信息。我们描述了这些技术的应用, 以确定小鼠的步态缺陷受自身免疫介导的鞘。这些方法也可以用来表征步态缺陷的其他小鼠模型的运动障碍。

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