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Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
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Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
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September 15, 2017
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Vascular endothelium tightly controls leukocyte recruitment. Inadequate leukocyte extravasation contributes to human inflammatory diseases. Therefore, searching for novel regulatory elements of endothelial activation is necessary to design improved therapies for inflammatory disorders. Here, we describe a comprehensive methodology to characterize novel endothelial regulators that can modify leukocyte trafficking during inflammation.
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Higueras, M. Á., Jiménez-García, L., Herranz, S., Hortelano, S., Luque, A. Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response. J. Vis. Exp. (127), e55824, doi:10.3791/55824 (2017).
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