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1Department of Anesthesiology,Ohio State University College of Medicine, 2Department of Anesthesiology and Pain Medicine,Nationwide Children’s Hospital, 3Department of Anaesthesia and Critical Care Medicine,University of Toronto, 4Department of Biomedical Sciences, Section of Anatomic Pathology,Cornell University College of Veterinary Medicine, 5Department of Pathology and Anatomy,Ohio State University College of Medicine, 6Department of Pathology and Laboratory Medicine,Nationwide Children’s Hospital
Chapters
- 00:05Title
- 00:45Preparing the Animal
- 02:49Femoral Artery Catheterization
- 04:11Collecting Data and Completing Surgery
- 05:30Results: Consistency and Reproducibility of Lab Values
- 06:07Conclusion
Anesteziye bağlı gelişme nörotoksisitesi (AIDN) araştırmaları, insanlar için geniş ölçüde uygulanmayan kemirgenler üzerine yoğunlaşmıştır. İnsan olmayan primat modelleri daha alakalı, ancak maliyet önleyici ve deney için kullanımı zor. Domuz yavrusu aksine, anestezik nörotoksisite çalışması için klinik açıdan önemli, pratik bir hayvan modeli idealdir.
Tags
Piglet ModelAnesthetic-induced Developmental Neurotoxicity (AIDN)Translational NeurosciencePhysiologic HomeostasisAnesthesia InductionPulse OximetryBlood PressureElectrocardiographyTemperatureTracheal IntubationLidocaineEnd-tidal Carbon DioxideOphthalmic OintmentAntibioticSterile FieldFemoral Neurovascular Bundle
