Journal
/
면역학 및 감염병학
/
がん抗原の機構理事T細胞受容体の認識を決定するためにX線結晶学、生物物理学、および機能アッセイを使用して、
JoVE 신문
면역학 및 감염병학
This content is Free Access.
JoVE 신문 면역학 및 감염병학
Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
Please note that all translations are automatically generated. Click here for the English version.

がん抗原の機構理事T細胞受容体の認識を決定するためにX線結晶学、生物物理学、および機能アッセイを使用して、

11,065 Views

•

09:53 min

•

February 06, 2017

DOI:

10.3791/54991-v

DOI:
10.3791/54991-v

•

09:53 min
February 06, 2017

•

2 Views
, , , , , , , ,
1Division of Infection and Immunity and Systems Immunity Research Institute,Cardiff University, 2Department of Oncology,University Hospital of Lausanne (CHUV), 3Ludwig Insitutue for Cancer Research, Lausanne Branch,University of Lausanne

Tags

X-ray CrystallographyBiophysicsFunctional AssaysT-cell ReceptorCancer AntigensT-cell ImmunologyReceptor-ligand InteractionsProtein RefoldingHLABeta 2-MTCR Alpha/beta ChainsAnion Exchange ChromatographyStructural AnalysisBiophysical AnalysisImmune ResponsesTherapyDiagnosis

Read Article

Cite this Article

MacLachlan, B. J., Greenshields-Watson, A., Mason, G. H., Schauenburg, A. J., Bianchi, V., Rizkallah, P. J., Sewell, A. K., Fuller, A., Cole, D. K. Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens. J. Vis. Exp. (120), e54991, doi:10.3791/54991 (2017).

Download .ris file

Copy

Share Video

.

Copy