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Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
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Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors

DOI:
10.3791/54873-v

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09:45 min

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April 27, 2017

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, ,
1Department of Chemistry,Technische Universität München

Chapters

  • 00:05Title
  • 00:59Synthesis of the Guanidinylation Precursors: Methylated Species
  • 02:30Synthesis of the Guanidinylation Precursors: Hexylamine-modified Species
  • 03:55Synthesis of the Guanidinylation Precursors: Acylated Species
  • 06:31Guanidinylation and Deprotection in Solution
  • 08:14Results: Synthesis of Alkyl-modified Guanidines
  • 09:11Conclusion

Summary

자동 번역

자동 번역

A protocol for the synthesis of alkyl-modified guanidines based on the use of the corresponding precursors is presented.

Tags

GuanidineFunctionalizationPeptidesIntegrin LigandsGPCR LigandsSPPSMolecular ImagingPersonalized MedicineBoc-pyrazol CarboxamaidinePPh3THFMethanolDiisopropyl AzodicarboxylateDCMSilica ColumnDde-6-Aminohexanol

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