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Ein Test zur Messung der Wirkung von Ethanol auf die Fortbewegungsgeschwindigkeit der<em> Caenorhabditis elegans</em
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An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans
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Ein Test zur Messung der Wirkung von Ethanol auf die Fortbewegungsgeschwindigkeit der<em> Caenorhabditis elegans</em

8,467 Views

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10:35 min

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April 09, 2015

DOI:

10.3791/52681-v

DOI:
10.3791/52681-v

•

10:35 min
April 09, 2015

•

4 Views
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1Department of Pharmacology and Toxicology,Virginia Commonwealth University, 2VCU Alcohol Research Center,Virginia Commonwealth University

Summary

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C. elegans is a useful model for studying the effects of ethanol on behavior. We present a behavioral assay that quantifies the effects of ethanol on the locomotion speed of crawling worms; both initial sensitivity and the development of acute functional tolerance to ethanol can be measured with this assay.

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Caenorhabditis ElegansEthanolLocomotionAssayBehavioral PlasticityInitial SensitivityAcute Functional Tolerance

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Davies, A. G., Blackwell, G. G., Raabe, R. C., Bettinger, J. C. An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans. J. Vis. Exp. (98), e52681, doi:10.3791/52681 (2015).

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