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An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans
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JoVE Journal 神経科学
An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans

An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans

8,467 Views

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10:35 min

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April 09, 2015

DOI:

10.3791/52681-v

DOI:
10.3791/52681-v

•

10:35 min
April 09, 2015

•

4 Views
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1Department of Pharmacology and Toxicology,Virginia Commonwealth University, 2VCU Alcohol Research Center,Virginia Commonwealth University

概要

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C. elegans is a useful model for studying the effects of ethanol on behavior. We present a behavioral assay that quantifies the effects of ethanol on the locomotion speed of crawling worms; both initial sensitivity and the development of acute functional tolerance to ethanol can be measured with this assay.

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Davies, A. G., Blackwell, G. G., Raabe, R. C., Bettinger, J. C. An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans. J. Vis. Exp. (98), e52681, doi:10.3791/52681 (2015).

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