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Optogenetische Stimulation des Hörnervs
1InnerEarLab, Department of Otolaryngology,University Medical Center Goettingen, 2Bernstein Focus for Neurotechnology,University of Goettingen, 3Auditory Systems Physiology Group, Department of Otolaryngology,University Medical Center Goettingen, 4Center for Nanoscale Microscopy and Molecular Physiology of the Brain,University of Goettingen, 5Department of Chemical, Electronic, and Biomedical Engineering,University of Guanajuato
Chapters
- 00:05Title
- 01:54Preparing the μLED Stimulator
- 03:31Cochleostomy for Transcochlear Stimulation
- 05:12Implanting the Stimulator and Recording Optogenetic Auditory Brainstem Responses (oABR)
- 07:40Recording Optically Evoked Local Field Potentials
- 08:21Results: Comapring Auditory Brainstem Response and Signal Propagation from oABR
- 09:46Conclusion
Cochlea-Implantate (CI) ermöglichen durch direkte elektrische Stimulation des Hörnervs zu hören. , Schlechte Frequenz und Intensität Auflösung begrenzt jedoch die Qualität der mit CIs zu hören. Hier beschreiben wir optogenetische Stimulation des Hörnervs bei Mäusen als alternative Strategie für auditive Forschung und Entwicklung künftiger CIs.
