The protocol aims at optimizing the construction and quality of tissue microarrays for biomarker research. It includes aspects of planning and design, digital pathology, virtual slide annotation, and automated tissue arraying.
Zlobec, I., Suter, G., Perren, A., Lugli, A. A Next-generation Tissue Microarray (ngTMA) Protocol for Biomarker Studies. J. Vis. Exp. (91), e51893, doi:10.3791/51893 (2014).