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JoVE Journal Neuroscience
Lukt Nervceller erhållits genom Nasal Biopsi Kombinerad med Laser-Capture Microdissection
 
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Lukt Nervceller erhållits genom Nasal Biopsi Kombinerad med Laser-Capture Microdissection: En Potentiell Approach att studera behandlingssvar hos psykiska störningar

Article DOI: 10.3791/51853-v • 08:33 min • December 4th, 2014
December 4th, 2014 •
1, 2, 1, 3, 2, 2, 4, 5, 1, 2
1Department of Psychiatry, Johns Hopkins University, 2Department of Psychiatry and Behavioral Sciences, Howard University, 3Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, 4Department of Psychiatry, Sheppard Pratt Hospital, 5Department of Psychiatry, Indiana University

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I denna studie, en ny plattform utreda intraneuronala molekylära signaturer behandlingssvar vid bipolär sjukdom (BD) har utvecklats och validerats. Luktepitel från BD patienter erhölls genom nasala biopsier. Sedan laser-capture microdissection kombinerades med realtid RT-PCR för att undersöka den molekylära tecknandet av litium svar i BD.

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Neurovetenskap bipolär sjukdom litiumterapi nasal biopsi luktepitel laser-capture microdissection realtids-PCR,
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