In vitro adherence assays can be used to study the attachment of Streptococcus pneumoniae to epithelial cell monolayers and to investigate potential interventions such as the use of probiotics for inhibiting pneumococcal colonization.
Dunne, E. M., Toh, Z. Q., John, M., Manning, J., Satzke, C., Licciardi, P. Investigating the Effects of Probiotics on Pneumococcal Colonization Using an In Vitro Adherence Assay. J. Vis. Exp. (86), e51069, doi:10.3791/51069 (2014).