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Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland
Chapters
- 00:05Title
- 01:16Pre-operative Preparation
- 02:48Intraductal Injection and Analysis of Mammary Gland Tissue
- 05:02Results: Mammary Gland Injections Enable Localized Delivery of Molecules
- 06:15Conclusion
A protocol for the non-invasive intraductal delivery of aqueous reagents to the mouse mammary gland is described. The method takes advantage of localized injection into the nipples of mammary glands targeting mammary ducts specifically. This technique is adaptable for a variety of compounds including siRNA, chemotherapeutic agents and small molecules.
