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使用操作性口面疼痛评估设备（OPAD）测量伤害行为的变化

JoVE 신문
행동분석학

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JoVE 신문 행동분석학

Use of the Operant Orofacial Pain Assessment Device (OPAD) to Measure Changes in Nociceptive Behavior

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使用操作性口面疼痛评估设备（OPAD）测量伤害行为的变化

20,738 Views

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12:20 min

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June 10, 2013

DOI:

10.3791/50336-v

DOI:

10.3791/50336-v

•

12:20 min

June 10, 2013

•

7 Views

Ethan M. Anderson^1,2, Richard Mills³, Todd A. Nolan⁴, Alan C. Jenkins⁴, Golam Mustafa¹, Chris Lloyd³, Robert M. Caudle^1,2, John K. Neubert⁴

¹Department of Oral and Maxillofacial Surgery,University of Florida College of Dentistry, ²Department of Neuroscience, McKnight Brain Institute,University of Florida College of Medicine , ³Stoelting Co., ⁴Department of Orthodontics,University of Florida

Summary

我们提出了一个用户友好的，高通量的操作性在清醒的，有意识的啮齿动物的疼痛行为的评价体系。颜面部疼痛评估设备（OPAD）可以评估疼痛通过奖励/冲突范式，从而提供了一种更人性化的方式测试。该协议将产生更多的临床相关数据和平移啮齿动物。

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